Fig. 3

Protective effect of the combination product and carbonates against cytotoxicity induced by low pH. Pretreatment of COLO-680 N with ground combination product tablets and corresponding amount of carbonates, but not of Opuntia extract attenuated acid-mediated cytotoxicity (3 h incubation at pH 3.0). Means ± SEM of mean values of 3 independently conducted studies. *p < 0.05, **p < 0.01, assessed by two-way ANOVA, followed by Dunnett´s test vs. medium pH 3.0.