Table 1 The baseline characteristics of subjects enrolled in this study were compared among groups stratified by the presence of cleft lip and cleft palate.
From: Alterations of senescence-associated markers in patients with non-syndromic cleft lip and palate
Characteristics | Total | CLO | CPO | CLP | p-value |
|---|---|---|---|---|---|
Patients | |||||
Total number (n) | 39 | 6 | 9 | 24 | - |
Age (months) | 12.9 (10.4–17.7) | 5.7 (4.4–10.0) | 12.9 (10.9–14.8) | 14.8 (11.5–18.0) | 0.643 |
Male (n,%) | 19 (48.7) | 2 (33.3) | 3 (33.3) | 14 (58.3) | 0.315 |
Body weight at first visit (kg) | 6.9 ± 3.1 | 6.6 ± 4.2 | 5.3 ± 2.1 | 7.6 ± 3.1 | 0.243 |
Family history of cleft lip/ cleft palate (n,%) | 1 (3.0) | 0 (0) | 0 (0) | 1 (5.0) | 0.715 |
Mothers | |||||
Total number (n) | 33 | 5 | 8 | 20 | - |
Age (year) | 30.0 ± 6.2 | 32.4 ± 6.2 | 27.6 ± 5.2 | 30.4 ± 6.7 | 0.386 |
Age ≥ 35 years (n, %) | 6 (17.7) | 1 (20.0) | 0 (0) | 5 (25.0) | 0.260 |
Current smoker (n,%) | 13 (39.4) | 0 (0) | 4 (50.0) | 9 (45.0) | 0.143 |
Folate supplement pre pregnancy (n,%) | 7 (21.2) | 2 (40.0) | 2 (25.0) | 3 (15.0) | 0.452 |
