Fig. 5
From: CuO nanoparticles for glioma treatment in vitro and in vivo
Effect of CuO NPs treatment on spatial recognition and memory ability in rats. (a) Changes of Melatonin (MLT) levels in rats hippocampus before and after treatment, (b) changes in hippocampus Oxytocin (OT), (c) changes in neurotransmitters γ-GABA, 5-HT, and Ach, (d) Marble burying test (MBT) the number of marble beads buried by rats, (e) Open field test (OFT) the moving distance of rats and (f) the stay time in the central area, (g) Habituation/dishabituation olfactory test (H/DOT) experiment of rats on a particular taste recognition, (H) Morris water maze experiment rats in the time duration of the platform in quadrant, (I) the escape latency in Morris water maze test, and (j) path tracing of rats in the Morris Water maze test. The number of parallel rats used in each experiment ranged from 6 to 8.
