Table 2 Comparisons of original volume obtained by automated segmentation methods.

From: Evaluating brain volume segmentation accuracy and reliability of FreeSurfer and Neurophet AQUA at variations in MRI magnetic field strengths

 

Lt.

Rt.

Neurophet AQUA

FreeSurfer

p

Neurophet AQUA

FreeSurfer

p

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

Cortical gray matter

218.0 ± 32.2

217.5 ± 31.9

0.816†

217.3 ± 31.5

217.3 ± 31.6

0.989†

Cerebral gray matter

245.6 ± 35.1

244.3 ± 35.2

0.578†

245.0 ± 34.5

244.4 ± 34.8

0.798†

Caudate

3.6 ± 0.5

3.5 ± 0.6

0.012

3.6 ± 0.6

3.6 ± 0.6

0.536†

Putamen

5.2 ± 0.7

4.6 ± 0.8

< 0.001

5.1 ± 0.8

4.7 ± 0.8

< 0.001

Pallidum

1.8 ± 0.3

2.0 ± 0.3

< 0.001

2.3 ± 0.3

1.9 ± 0.3

< 0.001

Thalamus

7.5 ± 1.0

7.0 ± 1.0

< 0.001

6.9 ± 0.9

7.0 ± 1.0

0.827†

Amygdala

1.6 ± 0.3

1.4 ± 0.4

< 0.001

1.8 ± 0.3

1.6 ± 0.3

< 0.001

Hippocampus

3.4 ± 0.5

3.8 ± 0.6

< 0.001

3.5 ± 0.5

3.9 ± 0.7

< 0.001

Inferior lateral ventricles

1.4 ± 0.9

0.9 ± 0.9

< 0.001

1.4 ± 0.8

0.9 ± 0.9

< 0.001

Cerebellum

67.3 ± 7.8

64.1 ± 7.9

< 0.001

66.5 ± 7.9

64.0 ± 8.0

< 0.001

Cerebral white matter

226.3 ± 26.9

216.5 ± 30.1

< 0.001

226.7 ± 27.2

215.6 ± 30.4

< 0.001

  1. The analysis encompassed MR images of all patients (426 MR images of 213 patients), irrespective of the magnetic field strength, for comparison if the volume distributions. The volume units are cm3. † Not statistically significant.
  2. Abbreviation: Lt, left hemisphere; Rt, right hemisphere; SD, standard deviation.