Fig. 2
(A) PCA scores plot, (B) OPLS-DA scores plot, and (C) important features (VIP-plot from OPLS-DA) distinguishing healthy controls and COVID-19 urine samples. Scaling was done to Pareto. R2X = 0.72, R2Y = 0.85, Q2 (cum) = 0.73, CV-ANOVA = 1.01 × 10− 21 for OPLS-DA model which was validated through Permutation Test (Figure S3). Important features (VIP > 1) plot shows those buckets that contain metabolites that increase (in red) or decrease (in blue) its content for each group.
