Fig. 3

Relations between clinical features and serum metabolite levels. (A) Scatterplot on correlation between serum glucose levels in COVID-19 patients and hospital time (R2 = 0.055, correlation coefficient (r) = 0.235, p-value < 0.05). Correlation analysis between clinical features and serum metabolite levels in COVID-19 patients (B) Considering MW and ICU groups together. (C) COVID-19 patients admitted to the MW. (D) COVID-19 patients admitted to the ICU. The color scale shows whether the relationship between two variables is positive (blue) or negative (violet). Spearman’s correlation coefficient was used for the analysis. Abbreviations: TAG: triacylglycerol, PC: phosphocholine, GPC: glycerophosphocholine, FA: fatty acids, PUFA: polyunsaturated FA, TMAO: trimethylamine, NAG: N-acetylglutamate, UFA: unsaturated FA, LDH: lactate dehydrogenase, IL-6: interleukin 6.