Table 1 Study set-up and sample size in experimental groups. Intervention abbreviations: ATT = Achilles tendon transection, FCA = free cage activity, PCM = paralysis of calf muscle, SO = steel- orthosis. End point = weeks after ATT.

From: Deprivation of loading during rat Achilles tendon healing affects extracellular matrix composition and structure, and reduces cell density and alignment

Group

ATT

FCA

PCM

SO

End point (Week)

N

Full loading (FL)

X

X

-

-

1, 2, 3, 12, 20

20 (4/week)

Reduced loading (RL)

X

X

X

-

1, 2, 3

12 (4/week)

Minimal loading (ML)

X

X

X

X

1, 2, 3

15 (5/week)

Intact tendon (IT)

-

X

-

-

-

4