Fig. 2

Differential expression of mRNAs and lncRNAs in the human retina dataset GSE160306. (A) Volcano plot of mRNA expression in dataset GSE160306-mRNA. The red triangles represent upregulated genes, the grey triangles represent nonsignificant genes, and the blue triangles represent downregulated genes. (B) Heatmap of DE-mRNAs expression in dataset GSE160306-mRNA. Vertical coordinates represent the 27 DE-mRNAs in the dataset GSE160306-mRNAs with the largest changes in expression. Each square in the graph represents the relative expression after Z-score transformation in the corresponding sample: red squares indicate genes with high expression, and the darker the red, the higher the gene expression level; blue squares indicate genes with low expression, and the darker the blue, the lower the gene expression level. The greater the color difference between the DR group and the control group, the greater the fluctuation in gene expression level. (C) Volcano plot of lncRNA expression in dataset GSE160306-lncRNA. The pink triangles represent upregulated genes, the grey triangles represent nonsignificant genes, and the green triangles represent downregulated genes. (D) Heatmap of DE-lncRNAs expression in dataset GSE160306-lncRNA. Vertical coordinates represent the 10 DE-lncRNAs in the dataset GSE160306-lncRNAs with the largest changes in expression. Pink squares indicate genes with high expression; green squares indicate genes with low expression. The greater the color difference between the DR group and the control group, the greater the fluctuation in gene expression level. DE-mRNAs differentially expressed mRNAs, DE-lncRNAs differentially expressed lncRNAs.