Fig. 5 | Scientific Reports

Fig. 5

From: Low to moderate ethanol exposure reduces astrocyte-induced neuroinflammatory signaling and cognitive decline in presymptomatic APP/PS1 mice

Fig. 5

[18F] Fluorodeoxyglucose uptake measured by in vivo microPET. (A) Representative FDG-PET images from air-exposed and ethanol-exposed presymptomatic APP/PS1 mice. The boundaries of ROIs were drawn on the coronal section. Glucose uptake increased in the cortex and hippocampus of ethanol exposed presymptomatic APP/PS1 mice. Quantification of glucose uptake by FDG-PET imaging in the cortex (B) and hippocampus (C). Data represent mean ± SEM; n = 10 per group. *P < 0.05 comparing each group. Two-tailed Mann–Whitney test. See Table S1 for full statistical information.

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