Fig. 3 | Scientific Reports

Fig. 3

From: Profiling of urinary extracellular vesicle protein signatures from patients with cribriform and intraductal prostate carcinoma in a cross-sectional study

Fig. 3The alternative text for this image may have been generated using AI.

Overview of regulated proteins for three pairwise comparisons. (A) Table summary of up- and down-regulated proteins applying a 0.05 adjusted P value and no threshold on effect size. The numbers in parenthesis represent regulated proteins with similar thresholds but applying regular P values. Volcano plots for the pairwise comparisons (B) non-IDC/non-Crib versus BPD, (C) IDC/Crib versus BPD, (D) cancer versus BPD, (E) ISUP ≥ 2 versus ISUP = 1 and (C) ISUP ≥ 2 versus ISUP = 1 considering adjustment of other clinical variables. Red horizontal line indicates 0.05 P value threshold. Red vertical lines indicate two-fold differential regulation. The number of regulated proteins indicated in the titles is based on P values and adjusted P values with an effect size greater than twofold.

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