Fig. 6

Functional enrichment analysis of cancer hallmark proteins based on significant regulated proteins for pairwise comparisons to control: Heatmap summarizing the functional enrichment of cancer hallmark proteins for each of the three pairwise comparisons to control based on (A) all regulated proteins, (B) up-regulated proteins and (C) down-regulated proteins. . Functional analysis based on significant regulated proteins for pairwise comparisons of different histological subgroups to non-IDC/non-Crib and cribriform: Functional enrichment against cancer hallmarks was performed for (D) all regulated proteins (p < 0.05), (E) all up-regulated proteins, and (F) all down-regulated proteins for each of the pairwise comparisons.