Table 2 Performance of LASSO-based Cox regression models for CIN3 + and cervical cancer prediction.

From: Nationwide study on development and validation of a risk prediction model for CIN3+ and cervical cancer in Estonia

Sample

Cohort 1

Cohort 2

Outcome (95% CI)

Cancer

CIN3+

Cancer

CIN3+

Harrell’s C

0.68 (0.67–0.69)

0.74 (0.73–0.75)

0.72 (0.68–0.76)

0.69 (0.68–0.70)

Harrell’s C cross-validated

0.67 (0.66–0.69)

0.74 (0.73–0.74)

0.67 (0.63–0.71)

0.68 (0.67–0.69)

AUROC 5 years

0.66

0.74

0.67

0.71

AUROC 8 years

0.68

0.72

0.67

0.68

Observed/expected 5 years

1.00 (0.94–1.07)

1.01 (0.98–1.04)

1.00 (0.83–1.19)

1.00 (0.95–1.04)

Observed/expected 8 years

1.00 (0.95–1.06)

1.03 (1.00–1.01)

1.00 (0.86–1.16)

1.00 (0.96–1.04)

Calibration slope

0.92 (0.84–1.00)

1.00 (0.97–1.02)

0.76 (0.59–0.93)

0.99 (0.94–1.03)

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