Table 2 Associations between inflammatory markers and BTMs in different models.

From: Divergent associations of inflammatory markers with bone turnover markers in elderly patients with osteoporotic fractures

 

P1NP

 

β-CTX

 

NLR

Model 1

β (95% CI) P-value

-1.0293 (-1.5627, -0.4960)

0.0002

-0.0112 (-0.0153, -0.0070)

< 0.0001

Model 2

β (95% CI) P-value

-1.0419 (-1.5776, -0.5062)

0.0001

-0.0114 (-0.0155, -0.0072)

< 0.0001

Model 3a

β (95% CI) P-value

-1.1788 (-1.7230, -0.6345)

< 0.0001

-0.0104 (-0.0145, -0.0062)

< 0.0001

MLR

Model 1

β (95% CI) P-value

-15.1813 (-25.1430, -5.2197)

0.0029

-0.1431 (-0.2210, -0.0653)

0.0003

Model 2

β (95% CI) P-value

-15.1736 (-25.1922, -5.1551)

0.0031

-0.1407 (-0.2189, -0.0626)

0.0004

Model 3b

β (95% CI) P-value

-17.4523 (-27.7335, -7.1710)

0.0009

-0.1327 (-0.2211, -0.0443)

0.0034

PLR

Model 1

β (95% CI) P-value

-0.0151 (-0.0458, 0.0156)

0.3363

0.0000 (-0.0002, 0.0002)

0.9811

Model 2

β (95% CI) P-value

-0.0159 (-0.0467, 0.0149)

0.3127

-0.0000 (-0.0002, 0.0002)

0.9673

Model 3c

β (95% CI) P-value

0.0326 (0.0007, 0.0645)

0.0458

0.0003 (0.0001, 0.0006)

0.0204

  1. Model 1: no covariates were adjusted.
  2. Model 2 was adjusted for age, sex, BMI, smoking and drinking.
  3. Model 3a was adjusted for age, sex, BMI, smoking, drinking, Ca, UA, CR, AST and Monocyte.
  4. Model 3b was adjusted for age, sex, BMI, smoking, drinking, Ca, UA, UN, CR, HDL and LDL.
  5. Model 3c was adjusted for age, sex, BMI, smoking, drinking, K, Mg, Na, P, Fibrinogen, Neutrophil, Apo A, HDL, Homocysteine, ALT and ASA.
  6. P1NP, procollagen type 1 N-terminal propeptide; β-CTX, β-C-terminal telopeptide of type I collagen; NLR, neutrophil-to-lymphocyte ratio; CI, confidence interval; MLR, monocyte-to-lymphocyte ratio; PLR, plateletto-lymphocyte ratio; BMI, body mass index; Ca, calcium; UA, uric acid; CR, creatinine; AST, aspartate aminotransferase; UN, urea nitrogen; HDL, high density lipoprotein; LDL, low density lipoprotein; K, potassium; Mg, magnesium; Na, sodium; P, phosphorus; Apo A, apolipoprotein A; ALT, alanine aminotransferase; ASA, the score of american society of anesthesiologists.
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