Fig. 1 | Scientific Reports

Fig. 1

From: The endoplasmic reticulum protein HSPA5/BiP is essential for decidual transformation of human endometrial stromal cells

Fig. 1The alternative text for this image may have been generated using AI.

Single cell expression of ER stress/UPR-associated genes during the decidualization process. (A) Schematic representation of in vitro decidualization of EnSCs and the progress of transcriptional states along time. (B) Expression of HSPA5, ATF6, ATF4, ERN1, EIF2AK3, TXNIP, DDIT3 and XBP1 was evaluated in silico on decidualizing EnSCs using scRNA sequencing data from Lucas et al.18. Color intensity indicates average gene expression, while circle size shows the percentage of cells expressing each gene. (C) Co-regulated decidual networks for HSPA5, ATF6, ATF4 and TXNIP. B2, C1, A1 and D indicates the gene clusters from Lucas et al.18.

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