Table 5 Comparison of genetic detection methods between NT thickening group and CH group.

From: Genetic correlation between fetal nuchal translucency thickening and cystic hygroma and exploration of pregnancy outcome

Method

NT

CH

X2

P

Positive

Negative

Total

Positive

Negative

Total

KA

17(9.8%)

157(90.2%)

174(100.0%)

11(26.8%)

30(73.2%)

41(100.0%)

8.525

<0.01#

CMA

23(13.2%)

151(86.8%)

174(100.0%)

17(41.5%)

24(58.5%)

41(100.0%)

17.481

<0.01#

WES

7(26.9%)

19(73.1%)

26(100.0%)

5(55.6%)

4(44.4%)

9(100.0%)

1.328

0.249

  1. NT, nuchal translucency; CH, cystic hygroma; KA, karyotype analysis; CMA, chromosome microarrary analysis; WES, whole exome sequencing; #, indicated significant difference.
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