Table 2 The distribution characteristics of related gene polymorphic genotypes in different lead exposed participants.
Gene polymorphism | N (%) | P-value | ||
|---|---|---|---|---|
Overall | Low lead exposure | High lead exposure | ||
NOTCH1 rs3124591 | 567 | 284 | 283 | 0.320 |
TT | 524(92.41) | 260(91.55) | 264(93.29) | |
CT | 39(6.88) | 23(8.10) | 16(5.65) | |
CC | 4(0.71) | 1(0.35) | 3(1.06) | |
CCM3 rs3804610 | 567 | 284 | 283 | 0.932 |
TT | 440(77.60) | 220(77.46) | 220(77.74) | |
CT | 120(21.16) | 60(21.13) | 60(21.20) | |
CC | 7(1.23) | 4(1.41) | 3(1.06) | |
VEGFR2 rs2305948 | 566 | 284 | 282 | 0.274 |
CC | 385(68.02) | 200(70.42) | 185(65.60) | |
CT | 164(28.98) | 74(26.06) | 90(31.91) | |
TT | 17(3.00) | 10(3.52) | 7(2.48) | |
HWE test P-value | ||||
NOTCH1 rs3124591 | 0.006 | 0.818 | 0.001 | |
CCM3 rs3804610 | 0.934 | 0.999 | 0.887 | |
VEGFR2 rs2305948 | 0.996 | 0.634 | 0.591 | |