Table 1 Univariate analysis of 106 patients with Carbapenem-Resistant-Klebsiella pneumonia bacteremia who received the ceftazidime-avibactam (CAZ-AVI) within 7 days of positive blood culture.
Survived n = 71 (67%) | Fatal n = 35 (33%) | p | |
|---|---|---|---|
Male gender | 44 (62) | 21 (60) | 0.845 |
Mean Age | 51 (sd: 17) | 59 (sd: 18) | 0.033 |
Mean Pitt bacteremia score | 4.1 (sd: 3.2) | 7 (sd: 2.6) | < 0.001 |
Charlson Comorbidity index | 5.2 (sd: 11.6) | 4.3 (sd: 2.7) | 0.648 |
Severe neutropenia | 12 (17) | 9 (26) | 0.284 |
Malignancy | 27 (38) | 14 (40) | 0.845 |
Mean initiation time of CAZ-AVI after blood culture collection (days) | 2.1 (sd: 1.9) | 2.9 (sd: 1.85) | 0.035 |
Patients initiated with CAZ-AVI on the day of blood culture was obtained | 23 (32.3) | 3 (8.5) | 0.007 |
