Table 4 Correlations between Hbb-related transcripts, plasma-IGF-I, glucose and HOMA-IR in running and sedentary mice.

From: Running in mice increases the expression of brain hemoglobin-related genes interacting with the GH/IGF-1 system

Correlations

Runner

Sedentary

(Spearman’s rho)

Igf1

Igf1r

Insr

Ghr

Igf1

Igf1r

Insr

Ghr

Hbb

rho

−0.38

−0.25

−0.074

−0.33

0.26

0.025

−0.19

0.037

 

p

0.023

0.14

0.67

0.048

0.12

0.88

0.27

0.83

 

N

36

36

36

36

36

36

36

36

Alas2

rho

−0.35

−0.27

−0.016

−0.34

0.33

0.047

−0.18

0.015

 

p

0.038

0.11

0.93

0.043

0.051

0.79

0.29

0.93

 

N

36

36

36

36

36

36

36

36

Alox15

rho

0.13

0.25

−0.095

0.49

−0.15

−0.23

−0.17

−0.005

 

p

0.47

0.17

0.60

0.004

0.43

0.22

0.37

0.98

 

N

33

33

33

33

32

32

32

32

Plasma-IGF1

rho

−0.16

−0.21

−0.36

−0.50

−0.12

−0.35

-0.40

0.20

 

p

0.36

0.25

0.042

0.003

0.50

0.049

0.022

0.26

 

N

33

33

33

33

33

33

33

33

Glucose

rho

-0.35

-0.37

0.31

−0.017

0.034

-0.10

-0.41

-0.018

 

p

0.044

0.036

0.078

0.92

0.86

0.60

0.024

0.92

 

N

33

33

33

33

30

30

30

30

HOMA-IR

rho

-0.33

-0.53

0.46

0.36

0.39

0.15

−0.14

−0.14

 

p

0.094

0.005

0.016

0.067

0.060

0.48

0.50

0.52

 

N

27

27

27

27

24

24

24

24

  1. The Spearman correlations are between the values for all values of all brain regions versus the levels of each transcript. Abbreviations are as in Table 1. and HOMA-IR is the homeostatic model of assessment of insulin resistance. N represents the pooled individual samples with successful analysis for all three brain regions. The reasons for not reaching N = 36 (i.e. missing numbers) are given in Tables 2, 3.
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