Fig. 7 | Scientific Reports

Fig. 7

From: Analysis for type of 53BP1 nuclear expression by immunofluorescence as an indicator of genomic instability in oropharyngeal squamous epithelial lesions

Fig. 7

Comparison of overall survival rate in p16INK4a–dependent and -independent oropharyngeal squamous cell carcinoma (A) and based on median incidences of abnormal type TP53-binding protein 1 (53BP1) expression with the cutoff value of 54.2% (B). P16INK4a–independent (p53–positive) cases show a worse prognosis compared with p16INK4a–dependent (p53–negative) cases. Cases exhibiting a high (> 54.2%) abnormal type 53BP1 expression show a worse prognosis compared with those exhibiting a low (< 54.2%) abnormal type 53BP1 expression. p-value < 0.01 by log-rank test.

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