Fig. 3 | Scientific Reports

Fig. 3

From: TLR3 activation enhances antitumor effects of sorafenib in hepatocellular carcinoma by activating NK cell functions through ERK and NF-κB pathways

Fig. 3

Poly(I: C) attenuated sorafenib-mediated suppression of NK cells in tumor-bearing C57BL/6 mice. (A) Percentages of CD3− and NK1.1+ NK cells in the spleen and peripheral blood were measured by flow cytometry. The data from five mice are presented as means± SDs. (B) Representative flow cytometry dot plots of NK cells in the spleen and peripheral blood of each group. (C) Percentages of CD3− and NK1.1+ NK cells in the spleen before and after magnetic-activated cell sorting. (D) The specific lysis of YAC-1 and Hepa1-6 cells by NK cells isolated from different groups (#P > 0.05, *P < 0.05; **P < 0.01; ***P < 0.001).

Back to article page