Fig. 1

GABPA expression was down-regulated in ccRCC. (A) Analysis of GABPA mRNA expression in TCGA-KIRC; (B) Survival analysis of TCGA data using GEPIA online software; (C) Representative H&E and IHC staining of the TMA of 60 ccRCC patients’ samples to show the histology and the protein level of GABPA in tumors or adjacent tissues; (D) The protein level of GABPA was detected by Western blot analysis in ccRCC cell lines and HK2 cells (n = 3); GAPDH was used as internal standards; ***indicates that compared with HK2 cells group; (E) The detection of the protein level of NAT10 by WB in 12 matched ccRCC tumor (C) and adjacent (N) tissues. The data were presented as mean SD. **P < 0.01, ***P < 0.001, ****P < 0.0001. Abbreviations: KDa, kilodalton; P1-P12, Patient 1-Patient 12.