Table 1 Clinical characteristics of patients.
Variables | DST-only (n = 518,901) | TC-1st (n = 801) | P-value | DST-1st (n = 744) | P-value |
|---|---|---|---|---|---|
Sex |  |  | < 0.001 |  | < 0.001 |
Male | 300,767(58.0%) | 250(31.2%) | Â | 299(40.2%) | Â |
Female | 218,134(42.0%) | 551(68.8%) | Â | 445(59.8%) | Â |
Age | 64(55–73) | 63(53-71.5) | 0.058 | 58(51–64) | < 0.001 |
Race | Â | Â | 0.036 | Â | 0.001 |
White | 397,982(76.7%) | 639(79.8%) | Â | 594 (79.8%) | Â |
Black | 64,609(12.5%) | 76(9.5%) | Â | 60(8.1%) | Â |
Other | 56,310(10.9%) | 86(10.7%) | Â | 90(12.1%) | Â |
Grade |  |  | < 0.001 |  | < 0.001 |
Grade I | 49,945(9.6%) | 92(11.5%) | Â | 101(13.6%) | Â |
Grade II | 235,849(45.5%) | 323(40.3%) | Â | 378 (50.8%) | Â |
Grade III | 102,223(19.7%) | 129(16.1%) | Â | 109(14.7%) | Â |
Grade IV | 8852(1.7%) | 7(0.9%) | Â | 12(1.6%) | Â |
Unknown | 122,032(23.5%) | 250(31.2%) | Â | 144(19.4%) | Â |
Summary stage |  |  | < 0.001 |  | < 0.001 |
Localized | 180,247(34.7%) | 357(44.6%) | Â | 351(47.2%) | Â |
Regional | 180,631(34.8%) | 254(31.7%) | Â | 303(40.7%) | Â |
Distant | 135,127(26.0%) | 167(20.8%) | Â | 70(9.4%) | Â |
Unknown | 22,896(4.4%) | 23(2.9%) | Â | 20(2.7%) | Â |
Histology | Â | Â | 0.662 | Â | 0.011 |
Adenocarcinoma | 377,994 (72.8%) | 589(73.5%) | Â | 573 (77.0%) | Â |
Other | 140,907(27.2%) | 212 (26.5%) | Â | 171 (23.0%) | Â |
Surgery | Â | Â | 0.002 | Â | 0.002 |
Yes | 354,458(68.3%) | 587 (73.3%) | Â | 685 (92.1%) | Â |
No | 164,443(31.7%) | 214 (26.7%) | Â | 59 (7.9%) | Â |
Radiation | Â | Â | 0.006 | Â | 0.469 |
Yes | 93,734(18.1%) | 115(14.4%) | Â | 142(19.1%) | Â |
None/Unknown | 425,167(81.9%) | 686(85.6%) | Â | 602(80.9%) | Â |
Chemotherapy | Â | Â | 0.038 | Â | 0.35 |
Yes | 236,634(45.6%) | 336(41.9%) | Â | 352(47.3%) | Â |
None/Unknown | 282,267(54.4%) | 465(58.1%) | Â | 392(52.7%) | Â |
Marital status |  |  | 0.006 |  | < 0.001 |
Married | 304,407(58.7%) | 508(63.4%) | Â | 483(64.9%) | Â |
Not married | 214,494(41.3%) | 293(36.6%) | Â | 261(35.1%) | Â |
The primary site |  |  | < 0.001 |  | < 0.001 |
Esophagus | 31,302(6.0%) | 23(2.9%) | Â | 16(2.2%) | Â |
Stomach | 58,509(11.3%) | 104(13.0%) | Â | 61(8.2%) | Â |
Small intestine | 16,040(3.1%) | 46(5.7%) | Â | 48(6.5%) | Â |
Colon | 224,388(43.2%) | 366(45.7%) | Â | 374(50.3%) | Â |
Rectum | 107,103(20.6%) | 157(19.6%) | Â | 199(26.7%) | Â |
Liver | 59,231(11.4%) | 75 (9.4%) | Â | 33 (4.4%) | Â |
Pancreas | 22,328(4.3%) | 30(3.7%) | Â | 13 (1.7%) | Â |
Survival months | 43(10–103) | 54(19-94.5) | 0.474 | 127(81-180.75) | < 0.001 |
Vital statu |  |  | < 0.001 |  | < 0.001 |
Alive | 174,177(33.6%) | 416(51.9%) | Â | 513(69.0%) | Â |
Death | 344,724(66.4%) | 385(48.1%) | Â | 231(31.0%) | Â |
Cause of death |  |  | < 0.001 |  | < 0.001 |
Alive | 174,177(33.6%) | 416(51.9%) | Â | 513(69.0%) | Â |
Digestive | 199,857(38.5%) | 197(24.6%) | Â | 102(13.7%) | Â |
Other | 144,717(27.9%) | 188(23.5%) | Â | 129(17.3%) | Â |
