Fig. 1 | Scientific Reports

Fig. 1

From: Deep phenotyping the right ventricle to establish translational MRI biomarkers for characterization of adaptive and maladaptive states in pulmonary hypertension

Fig. 1

Longitudinal assessment of RV and LV in male rats. (a) Experimental design and representative cardiac MRI images acquired at 0, 2-, and 4-weeks MCT (a) and 4-, 6-, 8-, 10-week SuHx (c). Cardiac MRI derived metrics to assess hypertrophy, dilatation, and systolic function of RV and LV in MCT (b) and SuHx rats (d). Results are presented as fold change from baseline values (mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, one-way ANOVA, comparison to healthy controls, Dunnett correction for multiple comparisons): 0-weeks (n = 12), 2-weeks MCT (n = 12), 4-weeks MCT (n = 9), 4-weeks SuHx (n = 7), 6-weeks SuHx (n = 15), 8-weeks SuHx (n = 10), 10-weeks SuHx (n = 10).

Back to article page