Table 2 Liver function indicators of patients before and after liver transplantation.

From: Identification of novel ABCB4 variants and genotype-phenotype correlation in progressive familial intrahepatic cholestasis type 3

 

Gender/Age (years)

Jaundice

Portal

hyperten-sion

Time

TBil*

µmol/L

0–25

DBil*

µmol/L

0–10

TBA*

µmo/ L

0–20

ALT*

U/L

0–40

AST*

U/L

0–40

ALP*

U/L

0-281

GGT*

U/L

0–58

Ceruloplasmin

mg/dL

15–45

State

Day

P1*

Female/

1.5

Yellow staining of the sclera

Splenomegaly

Before- LT*

Last test

47.9

26.9

235.6

82

238

247

126

47.77

Post-orthotopic- LT*

1d

67.6

43.9

/

497

540

97

44

/

2d

27.5

18.8

/

678

502

83

38

/

3d

17.7

10.3

/

448

229

78

140

/

4d

18.5

12.9

/

300

105

75

43

/

5d

20.6

14.6

37.4

212

59

103

49

17.17

8d

12.5

6.7

14.2

88

55

96

26

13.83

12d

4.4

2.7

5.9

62

68

80

41

18.59

14d

4

2.5

4.9

43

69

96

41

18.18

16d

3.9

1.4

7.2

32

47

103

38

25.01

18d

5

2.6

5.2

19

32

119

28

31.41

20d

3.7

1.3

5.6

15

29

128

19

/

P2*

Male/

23

Yellow staining of the sclera

Splenomegaly, varicose veins of the esophagus

Before- LT

Last test

628

465.3

260.6

40

80

154

53

25.16

Post-orthotopic- LT

1d

423.1

323.2

/

182

384

103

41

/

2d

195.7

160.5

10

161

169

90

38

25.27

3d

172.6

145.2

8.2

116

59

87

52

25.78

4d

148

124.6

32

93

38

99

113

27.38

5d

122.3

98.3

15

77

41

87

96

19.63

6d

130.7

102.1

29.9

69

37

103

110

20.46

7d

148.1

122.9

154.4

60

36

144

159

22.93

8d

156.7

130

179.8

50

29

186

173

22.74

9d

114.7

90.1

50.3

44

25

209

168

23.82

10d

79.3

66.4

21.8

73

57

169

135

20.44

11d

74.3

59.1

10.7

68

35

147

106

18.42

12d

65.8

55.5

32.4

54

19

135

95

18.23

155d

13.5

5.4

16.3

17

17

297

21

\

180d

10.3

5.2

12

10

14

363

20

\

216d

19.2

7.7

16.1

14

17

3113

17

\

  1. *TBil: Total serum bilirubin.DBil: Direct bilirubin.TBA: Total serum bile acid.ALT: Alanine transaminase. AST: Aspartate aminotransferase. ALP: Serum alkaline phosphatase. GGT: Serum gamma glutamyltransferase. P1: Patient 1.P2: Patient 2. LT: Liver transplantation.