Table 3 Time trend in aAARs of GB over the period 1993–2017 by sex (Standard: Europe 2013).

From: Epidemiology of malignant brain tumors in Genova, Italy. 1993–2017

Period

Male

Female

Both sexes

No.

CR

AAR

95%CI

No.

CR

AAR

95%CI

No.

CR

AAR

95%CI

1993–1995

28

2.12

2.64

1.54–3.75

23

1.55

1.63

0.96–2.31

51

1.82

2.02

1.45–2.59

1996–1998

41

3.19

3.91

2.60–5.22

30

2.08

2.13

1.36–2.90

71

2.60

2.85

2.17–3.53

1999–2001

45

3.59

4.07

2.81–5.33

33

2.34

2.32

1.53–3.11

78

2.92

3.07

2.38–3.76

2002–2004

47

3.81

4.31

3.03–5.59

38

2.73

2.77

1.87–3.66

85

3.24

3.46

2.71–4.21

2005–2007

47

3.80

4.32

3.03–5.61

39

2.81

2.89

1.98–3.80

86

3.28

3.52

2.76–4.28

2008–2010

55

4.48

4.91

3.59–6.23

43

3.11

3.15

2.21–4.10

98

3.76

4.00

3.20–4.79

2011–2013

52

4.24

4.41

3.20–5.63

37

2.69

2.72

1.84–3.61

89

3.42

3.53

2.79–4.26

2014–2017

65

4.04

4.23

3.19–5.28

44

2.45

2.46

1.73–3.20

109

3.20

3.30

2.67–3.92

Total

380

3.65

-

-

287

2.46

-

-

667

3.02

-

-

3YMPV

-

-

4.2

–0.9/9.5

-

-

5.1

–1.2/11.9

-

-

5.3

–0.4/11.3

  1. aAAR, age-adjusted incidence rate per 100,000 person-years (standard: Europe 2013); GB, glioblastoma; CI, confidence intervals; CR, crude incidence rate per 100,000 person-years; No., observed incident cases; 3YMPV, 3-year mean percent variation.