Table 5 Time trend in aAARs of NOS over the period 1993–2017 by sex (Standard: Europe 2013).

From: Epidemiology of malignant brain tumors in Genova, Italy. 1993–2017

Period

Male

Female

Both sexes

No.

CR

AAR

95%CI

No.

CR

AAR

95%CI

No.

CR

AAR

95%CI

1993–1995

27

2.05

2.76

1.63–3.90

27

1.82

2.26

1.40–3.13

54

1.93

2.54

1.83–3.24

1996–1998

29

2.25

4.02

2.43–5.63

39

2.70

3.04

2.06–4.02

68

2.49

3.38

2.54–4.22

1999–2001

36

2.87

4.65

2.97–6.34

36

2.55

2.87

1.91–3.84

72

2.70

3.55

2.70–4.41

2002–2004

24

1.95

3.01

1.71–4.32

39

2.80

3.13

2.14–4.12

63

2.40

3.11

2.32–3.90

2005–2007

27

2.19

3.24

1.88–4.60

36

2.59

2.75

1.84–3.66

63

2.40

2.91

2.17–3.66

2008–2010

30

2.44

3.23

1.99–4.47

36

2.61

2.59

1.72–3.45

66

2.53

2.87

2.15–3.58

2011–2013

33

2.69

3.78

2.43–5.12

34

2.47

2.52

1.67–3.37

67

2.58

3.03

2.30–3.76

2014–2017

52

3.23

4.58

3.31–5.85

48

2.68

2.67

1.91–3.43

100

2.94

3.39

2.73–4.05

Total

258

2.48

-

-

295

2.53

-

-

553

2.51

-

-

3YMPV

-

-

3.0

–4.1/10.6

-

-

–0.7

–4.6/3.3

-

-

0.8

–3.3/5.1

  1. aAAR, age-adjusted incidence rate per 100,000 person-years (standard: Europe 2013); NOS, non-otherwise specified malignancies; CI, confidence intervals; CR, crude incidence rate per 100,000 person-years; No., observed incident cases; 3YMPV, 3-year mean percent variation