Table 4 Comparison of the concordance rates between the HRM analysis and next-generation sequencing for the 5 variants Omicron.

From: Rapid detection of the SARS-CoV-2 omicron variants based on high-resolution melting curve analysis

Variants

BA.2.75

BA.5.2

BF.7

XBB.1

XBB.2

Positive concordance rate

100%(2/2)

100%(9/9)

80%(8/10)

86.4%(19/22)

100%(2/2)

Negative concordance rate

97.67(42/43)

94.4%(34/36)

100%(35/35)

100%(23/23)

95.4%(41/43)

  1. For the 2 samples with XBB as the HRM typing result, they were classified as false negatives in the XBB.1 concordance rate calculation and as false positives in the XBB.2 concordance rate calculation. For the sample with XBB.1 or BA.2.75 as the typing result, it was classified as false negative in the XBB.1 concordance rate calculation and as false positive in the BA.2.75 concordance rate calculation.
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