Fig. 1
From: Stenosing Crohn’s disease patients display gut autophagy/oxidative stress imbalance
The autophagic flux is reduced in CD patients. (a–b) We measured the mean levels of Lc3b-II expression in gut samples derived from control (Ctr), active inflammation (AI), stenosing (S) patients. Data show mean ± the standard error mean (SEM) (n = 9–12 independent samples); (c–d) P62 protein levels from Ctr, AI, and S pateints’ gut samples. Data show mean ± the standard error mean (SEM) (n = 5–7 independent samples); (e) p62 mRNA levels from Ctr, AI, and S pateints’ gut samples. Data show mean ± the standard error mean (SEM) (n = 3 independent samples); (f) graphic illustration of Crohn’s disease-associated inhibition of autophagy. *P < 0.05; **P < 0.01; ****P < 0.0001.
