Fig. 12

The molecular dynamics simulation results of epicatechin-URAT1, ellagic acid-URAT1, and epigallocatechin gallate-URAT1. (A) the RMSD of three complexes, (B) the RMSF of three complexes, (C) the Rg of three complexes, (D) the H-bonds of three complexes, (E) structures of three complexes before and after simulation, and (F) the binding mode of three complexes after simulation.