Fig. 3 | Scientific Reports

Fig. 3

From: Phyllanthi Fructus ameliorates hyperuricemia and kidney injure via inhibiting uric acid synthesis, modulating urate transporters, and alleviating inflammation

Fig. 3

Effects of YGZ extract on weight (A), viscera index (B), sUA (C), FBG (D), TCHO (E), TG (F), LDL-C (G), HDL-C (H), glucose curve (I), AUC0-2 h (J), Cr and BUN (K), SOD (L), MDA (M) in HUA rats (Supplementary Tables 1–6). Supplementation with YGZ extracts normalized the reduced weight gain in HUA rats induced by high-fat/high-sugar diet and PO/ADE oral administration, reversed the rise of liver and kidney indexes, reduced the concentrations of UA, FBG, TCHO,TG, LDL-C,Cr, BUN, and MDA, increased the level of HDL-C and the activities of SOD, and enhanced glucose tolerance. Data represented as mean ± SD of 6 rats. ###p < 0.001, ##p < 0.01, #p < 0.05 vs. CON group.***p < 0.001, **p < 0.01, *p < 0.05 vs. MOD group.

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