Table 5 Summarized key findings.

Age (as years, mean (SD))

54.1 (15.6)

47.9 (16.2)

59.9 (13.1)

Microbiology

Not identified* (n (%))

3 (11.1)

0 (0.0)

3 (21.4)

Gram-positive (n (%))

12 (44.4)

9 (69.2)

3 (21.4)

Gram-negative (n (%))

8 (29.6)

1 (7.7)

7 (50.0)

Mixed flora (n (%))

4 (14.8)

3 (23.1)

1 (7.1)

mRS at discharge

No symptoms (n (%))

0 (0.0)

0 (0.0)

0 (0.0)

No significant disability (n (%))

1 (3.7)

1 (7.7)

0 (0.0)

Slight disability (n (%))

4 (14.8)

3 (23.1)

1 (7.1)

Moderate disability (n (%))

4 (14.8)

2 (15.4)

2 (14.3)

Moderate-severe disability (n (%))

4 (14.8)

1 (7.7)

3 (21.4)

Severe disability (n (%))

9 (33.3)

3 (23.1)

6 (42.9)

Death (n (%))

5 (18.5)

3 (23.1)

2 (14.3)

CSF- WBC at Diagnosis (median [25^th percentile – 75^th percentile])

682 [246 – 2′944]

1181 [685 – 66′410]

346 [176 – 1′819]

CSF-WBC at IVT Initiation (median [25^th percentile – 75^th percentile])

596 [69 – 1′920]

511 [91 – 1′827]

680 [76 – 2′659]