Fig. 1

Voxel-wise differences between older expert meditators and older meditation-naive controls. The results are projected on medial and external 3D brain surface views of the MNI template. The clusters indicate areas where older expert meditators showed significantly greater (a) GMV, gray matter volume, and (b) perfusion than controls. Dark blue = bilateral inferior frontal gyrus (1), Green = left orbitofrontal cortex (2), Purple = bilateral posterior cingulate cortex (3), Pink = left temporal cluster (4), Light blue = left temporo-occipital cluster (5), Orange = right temporo-occipito-parietal cluster (6), Yellow = left temporo-parietal cluster (7). Results were evaluated for significance at puncorrected<0.005 combined with a minimum cluster size determined by Monte-Carlo simulations using the AFNI’s 3dClustSim program to achieve a corrected statistical significance of p < 0.05.