Fig. 6

Detection of the structural interaction between RH and cGAS or STING. (A) Molecular docking and dynamic simulation of RH-cGAS interaction. (a) Three-dimensional ribbon structure of the RH-cGAS complex. (b) Surface simulation model of the RH-cGAS complex in 0 and 100 ns. (c) RMSD of all atoms of cGAS and RH. (d) The SPR binding dissociation curve of RH-cGAS complex. (B) Molecular docking and dynamic simulation of RH-STING interaction. (a) Three-dimensional ribbon structure of the RH- STING complex. (b) Surface simulation model of the RH-STING complex in 0 and 100 ns. (c) RMSD of all atoms of STING and RH. (d) The SPR binding dissociation curve of RH-STING complex.