Table 1 Baseline clinical characteristics and MG relevant scores in both treatment groups.

From: Efgartigimod versus intravenous immunoglobulin in the treatment of patients with impending myasthenic crisis

Clinical characteristics

Efgartigimod (n = 9)

IVIg (n = 10)

P value

Sex, n (%)

 Female

7 (77.78%)

4 (40.00%)

0.170

 Male

2 (22.22%)

6 (60.00%)

Age at admission, years, mean ± SD

62.67 ± 19.30

55.10 ± 13.14

0.327

Age at onset, years, mean ± SD

61.33 ± 18.65

54.70 ± 13.08

0.378

Disease duration, months, mean ± SD

20.22 ± 26.20

6.80 ± 7.08

0.170

MGFA at administration, n (%)

 IIIb

5 (55.56%)

6 (60.00%)

1.000

 IVb

4 (44.44%)

4 (40.00%)

Thymoma

3 (33.33%)

3 (30.00%)

1.000

 Thymectomy

1 (11.11%)

0 (0.00%)

0.474

Antibody, n (%)

 AChR

9 (100.00%)

10 (100.00%)

0.857

 RyR

4 (44.44%)

3 (30.00%)

 Titin

4 (44.44%)

3 (30.00%)

Pyridostigmine at enrollment, n (%)

9 (100.00%)

9 (90.00%)

1.000

Immunosuppressive treatment at enrollment, n (%)

 Only tacrolimus

7 (77.78%)

6 (60.00%)

0.258

 Only prednisone

1 (11.11%)

1 (10.00%)

 Tacrolimus and prednisone

0 (0.00%)

3 (30.00%)

 Mycophenolate mofetil and prednisone

1 (11.11%)

0 (0.00%)

Baseline MG-ADL score, mean ± SD

13.78 ± 4.18

11.00 ± 3.62

0.139

Baseline MGC score, mean ± SD

26.44 ± 6.15

20.80 ± 7.16

0.084

  1. Legend: MG, myasthenia gravis; SD, standard deviation; MGFA, Myasthenia Gravis Foundation of America Classification; MG-ADL, Myasthenia Gravis Activities of Daily Living; MGC, Myasthenia Gravis Composite scale.