Table 2 The mean scores of the MG-ADL, MGC, QMG and MG-QOL15r at baseline and during follow-up in both treatment groups.

From: Efgartigimod versus intravenous immunoglobulin in the treatment of patients with impending myasthenic crisis

Clinical scores

Efgartigimod (n = 9)

*P value

IVIg (n = 10)

#P value

Baseline

MG-ADL score, mean ± SD

13.78 ± 4.18

11.00 ± 3.62

MGC score, mean ± SD

26.44 ± 6.15

20.80 ± 7.16

QMG score, mean ± SD

19.00 ± 5.03

MG-QOL15r score, mean ± SD

32.11 ± 9.33

Week 1

MG-ADL score, mean ± SD

7.11 ± 7.13

0.002

8.00 ± 3.40

 < 0.001

MGC score, mean ± SD

12.89 ± 12.34

0.004

15.00 ± 6.58

0.002

QMG score, mean ± SD

11.63 ± 6.74

0.001

MG-QOL15r score, mean ± SD

20.63 ± 15.78

0.017

Week 2

MG-ADL score, mean ± SD

5.57 ± 6.48

 < 0.001

MGC score, mean ± SD

11.50 ± 12.29

0.003

QMG score, mean ± SD

9.57 ± 7.64

0.002

MG-QOL15r score, mean ± SD

14.75 ± 15.10

0.003

Week 3

MG-ADL score, mean ± SD

4.25 ± 5.50

 < 0.001

MGC score, mean ± SD

10.13 ± 11.10

0.002

QMG score, mean ± SD

8.83 ± 8.50

0.010

MG-QOL15r score, mean ± SD

12.88 ± 12.74

0.001

Week 4

MG-ADL score, mean ± SD

2.67 ± 3.32

 < 0.001

4.20 ± 2.10

 < 0.001

MGC score, mean ± SD

7.22 ± 9.09

 < 0.001

7.30 ± 4.47

 < 0.001

QMG score, mean ± SD

7.67 ± 6.71

0.001

MG-QOL15r score, mean ± SD

8.88 ± 10.45

 < 0.001

  1. Legend: SD, standard deviation; MG-ADL, Myasthenia Gravis Activities of Daily Living; MGC, Myasthenia Gravis Composite scale; QMG, quantitative Myasthenia Gravis; MG-QOL15r, the revised 15-item Myasthenia Gravis Quality of Life questionnaire.
  2. *P value denotes the differences between baseline and post-intervention scores of MG-ADL, MGC, QMG, and MG-QOL15r in the efgartigimod group.
  3. #P value denotes the differences between baseline and post-intervention scores of MG-ADL, MGC, QMG, and MG-QOL15r in the IVIg group.