Table 1 Demographics and clinical characteristics of study participants.

From: Glycosylation changes of vWF in circulating extracellular vesicles to predict depression

 

Baseline

After follow-up in MDD cohort

HCs

MDD

p-value

MDD-DP

MDD-REM

p-value

Sample size

20

21

 

11

10

 

Age (y)

55.5 ± 7.6

57.6 ± 6.0

0.249

59.6 ± 5.6

56.5 ± 5.5

0.234

Male/Female

7/13

9/12

0.606

6/5

3/7

0.256

Onset age (y)

–

49.0 ± 12.7

–

53.0 ± 10.8

45.5 ± 13.4

0.200

HDRS

1.1 ± 1.0

23.8 ± 3.6

9.85e−27

22.4 ± 2.1

3.0 ± 2.2

2.16e−10

GAF

92.0 ± 4.3

51.2 ± 6.7

6.64e−24

53.0 ± 5.7

86.5 ± 7.8

2.69e−9

Antidepressants (equivalent dose of imipramine)

(mg)

–

220.1 ± 104.8

–

230.3 ± 100.7

209.3 ± 116.6

0.229

  1. Demographic data of healthy control participants (HCs) and patients with major depressive disorder (MDD). After the follow-up period in the MDD cohort, we determined a diagnosis of permanent depressive (MDD-DP) or remission state (MDD-REM). Data is presented as mean (standard deviation) or the number of participants in each group. Independent-samples t-test was performed for age, onset age, HDRS, GAF and antidepressant dose. Pearson’s Chi-square test was performed for number of male or female.
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