Fig. 6

Congo Red (CR) binding was performed to detect the amyloid fibrils in solution. The absorbance spectra of α-LA (0.2 mg mL−1) were obtained under different conditions, such as CR binding at pH 7.0 (
) and pH 2.0 (
) in the presence of 0.2 (
), 0.3 (
), and 0.5 (
) mM SHMP at pH 2.0. A fixed amount of CR (10 µM) was added to both the aggregated and nonaggregated samples and incubated for 30 min in the dark prior to the measurements.