Table 2 Predicted critical packing parameter for different phospholipid types and fatty acid compositions.
From: Spontaneous nanosized liposome formation from crude dried lecithin upon addition of glycerol
Fatty acid at sn-1 and sn-2 | Phospholipid | Critical packing parameter |
|---|---|---|
Phosphatidylcholine | ||
Linolenic–Linolenic | 0.96 | |
Linolenic–Linoleic | 0.92 | |
Linoleic–Linoleic | 0.84 | |
Oleic–Linoleic | 0.85 | |
Oleic–Oleic | 0.84 | |
Palmitic–Linoleic | 0.79 | |
Palmitic–Oleic | 0.80 | |
Palmitic–Palmitic | 0.73 | |
Phosphatidylethanolamine | ||
Linolenic–Linolenic | 1.10 | |
Linolenic–Linoleic | 1.10 | |
Linoleic–Linoleic | 1.00 | |
Oleic–Linoleic | 1.01 | |
Oleic–Oleic | 1.01 | |
Palmitic–Linoleic | 1.03 | |
Palmitic–Oleic | 1.01 | |
Palmitic–Palmitic | 1.03 | |
Phosphatidylinositol | ||
Linolenic–Linolenic | 0.77 | |
Linolenic–Linoleic | 0.77 | |
Linoleic–Linoleic | 0.81 | |
Oleic–Linoleic | 0.80 | |
Oleic–Oleic | 0.80 | |
Palmitic–Linoleic | 0.68 | |
Palmitic–Oleic | 0.75 | |
Palmitic–Palmitic | 0.59 | |
Phosphatidylserine | Protonated|Ionized | |
Linolenic–Linolenic | 1.14|1.00 | |
Linolenic-Linoleic | 1.14|0.97 | |
Linoleic–Linoleic | 1.16|0.96 | |
Oleic–Linoleic | 1.15|0.95 | |
Oleic–Oleic | 1.15|0.97 | |
Palmitic–Linoleic | 1.14|0.92 | |
Palmitic–Oleic | 1.14|0.98 | |
Palmitic–Palmitic | 1.10|0.97 | |
Phosphatidic Acid | ||
Linolenic–Linolenic | 0.89 | |
Linolenic–Linoleic | 0.88 | |
Linoleic–Linoleic | 0.84 | |
Oleic–Linoleic | 0.84 | |
Oleic–Oleic | 0.84 | |
Palmitic–Linoleic | 0.88 | |
Palmitic – Oleic | 0.93 | |
Palmitic–Palmitic | 0.94 | |
Phosphatidylglycerol | ||
Linolenic–Linolenic | 0.60 | |
Linolenic-Linoleic | 0.60 | |
Linoleic–Linoleic | 0.58 | |
Oleic–Linoleic | 0.58 | |
Oleic–Oleic | 0.60 | |
Palmitic–Linoleic | 0.56 | |
Palmitic–Oleic | 0.56 | |
Palmitic–Palmitic | 0.56 | |
Lyso-Phosphatidylcholine | ||
sn-2 Linolenic PC/sn-1 Linolenic PC | 0.20/0.21 | |
sn-2 Linoleic PC/sn-1 Linoleic PC | 0.20/0.22 | |
sn-2 Oleic PC/sn-1 Oleic PC | 0.23/0.23 | |
sn-2 Palmitic PC/sn-1 Palmitic PC | 0.20/0.22 | |
Lyso-Phosphatidylethanolamine | ||
sn-2 Linolenic PE/sn-1 Linolenic PE | 0.46/0.45 | |
sn-2 Linoleic PE/sn-1 Linoleic PE | 0.47/0.46 | |
sn-2 Oleic PE/sn-1 Oleic PE | 0.46/0.46 | |
sn-2 Palmitic PE/sn-1 Palmitic PE | 0.45/0.44 | |
Lyso-Phosphatidylinositol | ||
sn-2 Linolenic PI/sn-1 Linolenic PI | 0.060/0.090 | |
sn-2 Linoleic PI/sn-1 Linoleic PI | 0.060/0.092 | |
sn-2 Oleic PI/sn-1 Oleic PI | 0.064/0.092 | |
sn-2 Palmitic PI/sn-1 Palmitic PI | 0.064/0.100 | |
Lyso-Phosphatidylserine | Protonated|Ionized | |
sn-2 Linolenic PS/sn-1 Linolenic PS | 0.33/0.30|0.25/0.22 | |
sn-2 Linoleic PS/sn-1 Linoleic PS | 0.36/0.36|0.20/0.28 | |
sn-2 Oleic PS/sn-1 Oleic PS | 0.31/0.31|0.25/0.25 | |
sn-2 Palmitic PS/sn-1 Palmitic PS | 0.30/0.32|0.27/0.26 | |
Lyso-Phosphatidic Acid | ||
sn-2 Linolenic PA/sn-1 Linolenic PA | 0.46/0.44 | |
sn-2 Linoleic PA/sn-1 Linoleic PA | 0.42/0.40 | |
sn-2 Oleic PA/sn-1 Oleic PA | 0.40/0.40 | |
sn-2 Palmitic PA/sn-1 Palmitic PA | 0.39/0.38 |
