Fig. 1 | Scientific Reports

Fig. 1

From: Using parenclitic networks on phaeochromocytoma and paraganglioma tumours provides novel insights on global DNA methylation

Fig. 1The alternative text for this image may have been generated using AI.

Venn diagram presenting the overlap in the genes associated with differentially methylated loci and regions using two different methods, dmpFinder and bumphunter. The two methods have been applied to identify differentially methylated CG loci or regions respectively between aggressive and non-aggressive, and metastatic and non-metastatic PPGL cases. The first comparison is denoted with “aggressive” and the latter with “metastatic”. When comparing aggressive to non-aggressive the results of the two methods show no overlap. Also when comparing metastatic to non-metastatic the overlap is small. In addition, the two comparisons for the same method showed limited overlap despite the large overlap of the metastatic and aggressive cases.

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