Fig. 5 | Scientific Reports

Fig. 5

From: Using parenclitic networks on phaeochromocytoma and paraganglioma tumours provides novel insights on global DNA methylation

Fig. 5The alternative text for this image may have been generated using AI.

Boxplots of the beta values for aggressive (in blue) and non-aggressive (in orange) samples on the candidate CG loci. The differences between aggressive and non-aggressive per CG locus have been tested using the Mann-Whitney statistical test and the significance is indicated in the top of each plot, with “ns” implying no significant differences in the beta values between aggressive and non-aggressive and * indicating a p-value less than 0.05. Only one locus displays significant differences. This is expected because the parenclitic network approach identifies CG loci, variation in which is likely to have a widespread effect in the methylation, instead of CG loci with locus-specific differences in DNA methylation.

Back to article page