Fig. 1 | Scientific Reports

Fig. 1

From: SALL4 mediates SHP2 inhibition in myocardial fibroblasts through the DOT1L/H3K79me2 signaling pathway to promote the progression of myocardial infarction

Fig. 1

Impact of SALL4 on Cardiac Function in Mice with Myocardial Infarction. A: Differential gene volcano plots and horizontal scatter plots of SALL4 and DOT1L expression; B: Western blot detection of SALL4 expression in core myofibroblasts of cardiomyocytes in normal and myocardial infarcted mice; GAPDH as control protein; C: Ultrasound images of mice and statistics of EF, FS, LVAW;d, LVAW;s, LVID;d, and LVID;s. Data are expressed as mean + standard deviation. N = 8; **P < 0.01; *P < 0.05; nsP > 0.05.

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