Table 4 IC50 values of F. Vulgare Miller var. Dulce fruit oil samples compared to doxorubicin against two human cell carcinoma:

From: Influence of ethephon and soil treatments on the essential oil composition of sweet fennel and its biological activities

Cell type

Mean IC50 ± S.D

Doxorubicin

Control

C1

C2

C3

C4

HepG2

0.343 ± 0.0873

1.39 ± 0.0157

7.56 ± 0.402***, aaa

9.50 ± 0.898***, aaa

15.1 ± 2.21***, aaa

8.28 ± 1.18***, aaa

PC-3

3.18 ± 0.770

2.89 ± 0.0623

5.01 ± 0.837

11.0 ± 1.29***, aaa

8.43 ± 0.663***, aaa

5.31 ± 0.950 a

  1. Data expressed as the mean value of 50% inhibitory concentration (IC50 in µg/ml) ± S.D, C1-4 = Conditions 1–4.
  2. * Level of significance compared to doxorubicin: ***: p < 0.001, ** : p < 0.01, * p < 0.05.
  3. aLevel of significance compared to (control): aaa: p < 0.001, aa: p < 0.01, a : p < 0.05.
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