Table 4 Comparison of neuropsychological test scores between HPPD group and non-using controls utilising Mann Whitney U Test (n = 16, 95% CI) and FDR alpha adjustment.
HPPD M(SD) (n = 8) | Non-using control M(SD) (n = 8) | HPPD vs. non-using control | Adjusted p-values | |
|---|---|---|---|---|
WAIS IV | ||||
Digit-symbol | 61.1 (6.9) | 72.6 (10.0) | W = 8, p = 0.013 | pa = 0.346 |
Symbol search | 39.1 (4.8) | 44.9 (7.9) | W = 16.5, p = 0.114 | pa = 0.591 |
WMS IIIR | ||||
Digit span, forwards | 9.1 (1.6) | 8.8 (1.5) | W = 38.5, p = 0.517 | pa = 0.795 |
Digit span, backwards | 8.1 (2.0) | 8.6 (2.3) | W = 28, p = 0.711 | pa = 0.888 |
WMS IV | ||||
Logical memory-immediate recall | 17.6 (2.2) | 18.3 (2.2) | W = 27, p = 0.634 | pa = 0.867 |
Logical memory-delayed recall | 15.2 (2.8) | 16.1 (3.4) | W = 25, p = 0.493 | pa = 0.795 |
Rey-Osterrieth Complex Figure* | ||||
Figure copy | 35.5 (0.5) | 34.1 (2.0) | W = 42, p = 0.099 | pa = 0.591 |
Immediate recall | 21.1 (5.1) | 19.6 (7.0) | W = 35, p = 0.451 | pa = 0.795 |
Delayed recall | 19.9 (6.8) | 20.4 (6.5) | W = 26.5, p = 0.908 | pa = 0.983 |
Stroop Test | ||||
Word reading time (s) | 28 (2.7) | 26.4 (2.1) | W = 44, p = 0.204 | pa = 0.795 |
Colour naming time (s) | 45.5 (5.1) | 42.9 (3.7) | W = 42.5, p = 0.291 | pa = 0.795 |
Interference time (s) | 64 (8.9) | 58.9 (4.7) | W = 42, p = 0.317 | pa = 0.795 |
Trail Making Test | ||||
Trail A time (s) | 26.9 (11.1) | 28.9 (6.9) | W = 24, p = 0.431 | pa = 0.795 |
Trail B time (s) | 68.8 (24.4) | 46.3 (9.9) | W = 49, p = 0.083 | pa = 0.591 |
WCST (64 Items)* | ||||
Total correct | 47.4 (8.8) | 49.9 (10.4) | W = 22, p = 0.520 | pa = 0.795 |
Perseverative errors | 6.8 (3.8) | 7.3 (4.3) | W = 25.5, p = 0.815 | pa = 0.921 |
Non-perseverative errors | 10.6 (8.6) | 7.6 (6.2) | W = 33, p = 0.600 | pa = 0.866 |
Categories completed | 3 (2.1) | 3.9 (2.0) | W = 22, p = 0.454 | pa = 0.795 |
TAP, alertness | ||||
Reaction time without warning (ms) | 244 (17.5) | 248.5 (19.8) | W = 23.5, p = 0.400 | pa = 0.795 |
Reaction time with warning (ms) | 242.8 (15.7) | 242.3 (23.5) | W = 32, p = 0.958 | pa = 0.996 |
TAP, divided attention | ||||
Auditory reaction time (ms) | 529 (68.7) | 571.5 (68.3) | W = 22, p = 0.328 | pa = 0.795 |
Visual reaction time (ms) | 749.1 (55.5) | 721 (32.2) | W = 42, p = 0.328 | pa = 0.795 |
Tower of London | 17.5 (1.5) | 17.3 (1.7) | W = 35.5, p = 0.740 | pa = 0.888 |
Regensburger Word Fluency | ||||
Semantic category | 23.5 (6.1) | 29.3 (6.3) | W = 15.5, p = 0.092 | pa = 0.591 |
Categorical switching | 16 (3.3) | 15.5 (2.9) | W = 35.5, p = 0.751 | pa = 0.888 |