Table 4 Comparison of neuropsychological test scores between HPPD group and non-using controls utilising Mann Whitney U Test (n = 16, 95% CI) and FDR alpha adjustment.

From: Neuropsychological profiles of patients suffering from hallucinogen persisting perception disorder (HPPD): A comparative analysis with psychedelic-using and non-using controls

 

HPPD M(SD)

(n = 8)

Non-using control

M(SD)

(n = 8)

HPPD vs. non-using control

Adjusted p-values

WAIS IV

Digit-symbol

61.1 (6.9)

72.6 (10.0)

W = 8, p = 0.013

pa = 0.346

Symbol search

39.1 (4.8)

44.9 (7.9)

W = 16.5, p = 0.114

pa = 0.591

WMS IIIR

Digit span, forwards

9.1 (1.6)

8.8 (1.5)

W = 38.5, p = 0.517

pa = 0.795

Digit span, backwards

8.1 (2.0)

8.6 (2.3)

W = 28, p = 0.711

pa = 0.888

WMS IV

Logical memory-immediate recall

17.6 (2.2)

18.3 (2.2)

W = 27, p = 0.634

pa = 0.867

Logical memory-delayed recall

15.2 (2.8)

16.1 (3.4)

W = 25, p = 0.493

pa = 0.795

Rey-Osterrieth Complex Figure*

Figure copy

35.5 (0.5)

34.1 (2.0)

W = 42, p = 0.099

pa = 0.591

Immediate recall

21.1 (5.1)

19.6 (7.0)

W = 35, p = 0.451

pa = 0.795

Delayed recall

19.9 (6.8)

20.4 (6.5)

W = 26.5, p = 0.908

pa = 0.983

Stroop Test

Word reading time (s)

28 (2.7)

26.4 (2.1)

W = 44, p = 0.204

pa = 0.795

Colour naming time (s)

45.5 (5.1)

42.9 (3.7)

W = 42.5, p = 0.291

pa = 0.795

Interference time (s)

64 (8.9)

58.9 (4.7)

W = 42, p = 0.317

pa = 0.795

Trail Making Test

Trail A time (s)

26.9 (11.1)

28.9 (6.9)

W = 24, p = 0.431

pa = 0.795

Trail B time (s)

68.8 (24.4)

46.3 (9.9)

W = 49, p = 0.083

pa = 0.591

WCST (64 Items)*

Total correct

47.4 (8.8)

49.9 (10.4)

W = 22, p = 0.520

pa = 0.795

Perseverative errors

6.8 (3.8)

7.3 (4.3)

W = 25.5, p = 0.815

pa = 0.921

Non-perseverative errors

10.6 (8.6)

7.6 (6.2)

W = 33, p = 0.600

pa = 0.866

Categories completed

3 (2.1)

3.9 (2.0)

W = 22, p = 0.454

pa = 0.795

TAP, alertness

Reaction time without warning (ms)

244 (17.5)

248.5 (19.8)

W = 23.5, p = 0.400

pa = 0.795

Reaction time with warning (ms)

242.8 (15.7)

242.3 (23.5)

W = 32, p = 0.958

pa = 0.996

TAP, divided attention

Auditory reaction time (ms)

529 (68.7)

571.5 (68.3)

W = 22, p = 0.328

pa = 0.795

Visual reaction time (ms)

749.1 (55.5)

721 (32.2)

W = 42, p = 0.328

pa = 0.795

Tower of London

17.5 (1.5)

17.3 (1.7)

W = 35.5, p = 0.740

pa = 0.888

Regensburger Word Fluency

Semantic category

23.5 (6.1)

29.3 (6.3)

W = 15.5, p = 0.092

pa = 0.591

Categorical switching

16 (3.3)

15.5 (2.9)

W = 35.5, p = 0.751

pa = 0.888

  1. *N = 15 (7 non-using controls assessed), bold values = significant results, a p-values after alpha adjustment.