Table 5 Comparison of neuropsychological test scores between HPPD group and psychedelic-using controls utilising Mann Whitney U Test (n = 16, 95% CI) and FDR alpha adjustment.
HPPD M(SD) (N = 8) | Psychedelic-using-control M(SD) (N = 8) | HPPD vs. psychedelic-using control | Adjusted p-values | |
|---|---|---|---|---|
WAIS IV | ||||
Digit-symbol | 61.1 (6.9) | 64.6 (7.0) | W = 24.5, p = 0.461, | pa = 0.705 |
Symbol search | 39.1 (4.8) | 44 (3.6) | W = 13, p = 0.051 | pa = 0.372 |
WMS IIIR | ||||
Digit span, forwards | 9.1 (1.6) | 8.1 (1.6) | W = 44, p = 0.217 | pa = 0.625 |
Digit span, backwards | 8.1 (2.0) | 7.9 (2.2) | W = 35, p = 0.789 | pa = 0.894 |
WMS IV | ||||
Logical memory-immediate recall | 17.6 (2.2) | 17.3 (2.7) | W = 35, p = 0.791 | pa = 0.894 |
Logical memory-delayed recall | 15.2 (2.8) | 16.1 (2.7) | W = 25.5, p = 0.525 | pa = 0.758 |
Rey-Osterrieth Complex Figure* | ||||
Figure copy | 35.5 (0.5) | 33.8 (2.6) | W = 32, p = 0.293 | pa = 0.689 |
Immediate recall | 21.1 (5.1) | 21.5 (4.3) | W = 22.5, p = 0.900 | pa = 0.916 |
Delayed recall | 19.9 (6.8) | 21.2 (4.9) | W = 21, p = 0.746 | pa = 0.894 |
Stroop Test | ||||
Word reading time (s) | 28 (2.7) | 26.5 (3.0) | W = 40.5, p = 0.396 | pa = 0.689 |
Colour naming time (s) | 45.5 (5.1) | 40.6 (1.6) | W = 49, p = 0.081 | pa = 0.422 |
Interference time (s) | 64 (8.9) | 57.3 (6.2) | W = 46.5, p = 0.14 | pa = 0.524 |
Trail Making Test | ||||
Trail A time (s) | 26.9 (11.1) | 24.3 (6.9) | W = 34, p = 0.875 | pa = 0.916 |
Trail B time (s) | 68.8 (24.4) | 43.8 (6.4) | W = 52, p = 0.040 | pa = 0.372 |
WCST (64 Items) | ||||
Total correct | 47.4 (8.8) | 54.6 (3.4) | W = 13.5, p = 0.057 | pa = 0.372 |
Perseverative errors | 6.8 (3.8) | 5.8 (2.0) | W = 33.5, p = 0.916 | pa = 0.916 |
Non-perseverative errors | 10.6 (8.6) | 3.6 (2.1) | W = 51.5, p = 0.044 | pa = 0.372 |
Categories completed | 3 (2.1) | 4.6 (0.7) | W = 20, p = 0.161 | pa = 0.524 |
TAP, alertness | ||||
Reaction time without warning (ms) | 244 (17.5) | 238.4 (17.6) | W = 36.5, p = 0.673 | pa = 0.894 |
Reaction time with warning (ms) | 242.8 (15.7) | 232.6 (17.1) | W = 40, p = 0.442 | pa = 0.705 |
TAP, divided attention | ||||
Auditory reaction time (ms) | 529 (68.7) | 507.9 (74.4) | W = 41, p = 0.382 | pa = 0.689 |
Visual reaction time (ms) | 749.1 (55.5) | 749.4 (99.4) | W = 36, p = 0.713 | pa = 0.894 |
Tower of London | 17.5 (1.5) | 16.6 (1.6) | W = 42, p1 = 0.295 | pa = 0.689 |
Regensburger Word Fluency | ||||
Semantic category | 23.5 (6.1) | 29.5 (7.2) | W = 18, p = 0.154 | pa = 0.524 |
Categorical switching | 16 (3.3) | 13.3 (5.0) | W = 40.5, p = 0.397 | pa = 0.689 |
