Table 6 System suitability parameters of the proposed HPLC method for the determination of AZT, FP and OXY in nasal mucosa.

From: Validated HPLC method for simultaneous determination of azelastine hydrochloride fluticasone propionate and oxymetazoline in nasal mucosa and nasopharyngeal swabs from real human samples

Parameters

Values

Reference

AZT

FP

OXY

Retention time (min)

6.61

9.81

2.45

 

Capacity factor (k,)

7.92

12.16

2.21

K’ > 2.00

Tailing factor (T)

0.97

0.97

1.08

T ≤ 2.00

Number of theoretical plates (N)

8033

3596

5440

N > 2000

Height equivalent to theoretical plates (HETP)

0.03

0.06

0.04

The smaller the value, the higher the column efficiency

Selectivity

3.58

1.53

-

ɑ > 1.00

Resolution (RS)

-

20

7.2

RS > 1.50