Table 6 System suitability parameters of the proposed HPLC method for the determination of AZT, FP and OXY in nasal mucosa.
Parameters | Values | Reference | ||
|---|---|---|---|---|
AZT | FP | OXY | ||
Retention time (min) | 6.61 | 9.81 | 2.45 | |
Capacity factor (k,) | 7.92 | 12.16 | 2.21 | K’ > 2.00 |
Tailing factor (T) | 0.97 | 0.97 | 1.08 | T ≤ 2.00 |
Number of theoretical plates (N) | 8033 | 3596 | 5440 | N > 2000 |
Height equivalent to theoretical plates (HETP) | 0.03 | 0.06 | 0.04 | The smaller the value, the higher the column efficiency |
Selectivity | 3.58 | 1.53 | - | ɑ > 1.00 |
Resolution (RS) | - | 20 | 7.2 | RS > 1.50 |