Table 9 Nasopharyngeal swabs of real samples obtained at different interval times (results were expressed as mean concentration in swab± %RSD).

From: Validated HPLC method for simultaneous determination of azelastine hydrochloride fluticasone propionate and oxymetazoline in nasal mucosa and nasopharyngeal swabs from real human samples

Time (hours)

AZT

FP

OXY

Average concentration in nasopharyngeal swabs (µg/mL)

% RSD

Average concentration nasopharyngeal swabs (µg/mL)

%RSD

Average concentration nasopharyngeal swabs (µg/mL)

%RSD

Immediately

126.55

4.55

49.72

1.20

50.74

1.65

1

123.89

2.18

50.76

7.25

49.18

4.56

2

117.43

1.78

49.71

5.15

49.18

1.00

3

115.01

3.46

47.87

9.49

48.17

5.49

4

104.35

3.51

46.20

1.70

46.74

9.19

5

61.86

5.30

34.48

2.29

20.67

7.58

6

33.69

7.97

26.84

7.01

16.70

5.60

7

8.62

9.97

21.55

8.96

10.70

4.30

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