Table 2 Univariate analysis of blood parameters related to oxidative, metabolic, and inflammatory stress on Day 21 (D21).

From: Shortening of the telomere length during the transition period of dairy cows in relation to biological stress

Variable (unit)

Estimate ± Std. Error

P-value

P-value*

R2**

Note

Oxidative parameters

 GSSG (GSSG/GSH + GSSG)

0.005 ± 0.0015

0.001

0.005

0.08

1

 GPx (µmol/(min·mL plasma))

− 0.828 ± 0.2354

0.004

0.005

0.08

2

 MDA (nmol/g plasma)

0.008 ± 0.0063

0.352

0.9250

0.06

3

 ORAC (µM Trolox eq.)

− 0.0007 ± 0.00192

0.850

1.0000

0.06

4

 SOD (U/mL plasma)

− 0.0001 ± 0.00047

0.666

1.0000

0.06

4

Metabolic parameters

 AG ratio (A:G)

− 0.152 ± 0.0413

0.007

0.008

0.13

5

 Albumin (%)

− 0.004 ± 0.0012

0.007

0.008

0.13

6

 α-globulin (%)

0.017 ± 0.0036

0.0004

0.0008

0.16

4

 β-globulin (%)

0.012 ± 0.0046

0.009

0.012

0.10

7

 γ-globulin (%)

0.001 ± 0.0011

0.366

1.00

0.08

6

 Total protein (g/L)

0.0008 ± 0.00037

0.524

1.00

0.07

3

 Urea (mmol/L)

0.013 ± 0.0102

0.609

1.00

0.06

3

 AST (IU/L)

1.86 e-05 ± 3.168 e-04

0.520

1.00

0.06

4

Inflammatory parameters

 SAA (μg/mL)

2.80 e-04 ± 8.976 e-05

0.004

0.02

0.11

4

 Hp (mg/mL)

0.040 ± 0.0131

0.032

0.04

0.11

8

  1. The results shown are from the univariable model associated with the outcome variable Δ-TL (telomere length before parturition – telomere length after parturition). Disease and parity were forced into the model, while season and BCS were offered and retained when P < 0.1 (see Note). (N = 61).
  2. *P-value after multiple testing, using the Bonferroni correction (p.adjust () function).
  3. **The multiple R-squared.
  4. 1. Model covariate is BCS (P < 0.05).
  5. 2. Model covariate is season (P < 0.05).
  6. 3. Model covariates are BCS and season (P < 0.05 and P < 0.01, respectively).
  7. 4. Model covariates are BCS and season (P < 0.05).
  8. 5. Model covariates are BCS and season (P < 0.005 and P < 0.0005, respectively).
  9. 6. Model covariates are BCS and season (P < 0.005).
  10. 7. Model covariate is BCS (P < 0.005).
  11. 8. Model covariates are BCS and season (P < 0.005 and P < 0.05, respectively).