Fig. 5 | Scientific Reports

Fig. 5

From: Progressive histological and behavioral deterioration of a novel mouse model of secondary hydrocephalus after subarachnoid hemorrhage

Fig. 5

Acute and progressive white matter damage in mice after SAH. (a, b) Representative images of immunofluorescence staining for MBP in the corpus callosum in each group on days 3 and 28 post-SAH; scale bar = 50 µm. (c): Comparison of the MBP fluorescence intensity in the corpus callosum of the different group on days 3 post-SAH(n = 6). (d): Comparison of the MBP fluorescence intensity in the corpus callosum of the different group on days 28 post-SAH(n=6). (e) Representative images of silver staining of the corpus callosum of each group on days 3 and 28 post-SAH; scale bar = 50 µm. (f) TEM of neuronal and myelin ultrastructural alterations in the corpus callosum on days 3 and 28 post-SAH; scale bar = 1.0µm. The values are presented as the means ± SDs. *: p < 0.05 versus the sham group; #<0.05 versus the Single 60 group; one-way ANOVA followed by the least significant difference test. DAPI: 4’,6-diamidino-2’-phenylindole; MBP: myelin basic protein.

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