Fig. 4
EGCG alleviated brain damage caused by ICH in a collagenase rat model. (A–C) Representative images of hemorrhagic lesions, HE staining, and Cresyl Violet staining in rats from different groups. (D) Transmission electron microscopy was used to assess mitochondrial morphology in rats from different groups. (E) Volume quantification of hemorrhagic lesions (n = 4). (F) Nissl staining was performed to evaluate neuronal survival in rats from different groups (n = 4). (G) Brain water content was measured in each group to assess the effect of treatment on brain edema (n = 12). Scale bars: B, C 200/100µm; D 4/1µm. Data were expressed as mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
