Fig. 7

EGCG treatment significantly reduces iron death and apoptosis in primary cortical neurons through the Keap1/P62/Nrf2 pathway. (A) Protein expression levels of Keap1, P62, Nrf2, GPX4, XCT, BAX, BCL-2, and CASP3 were analyzed using Western blot. (B–J) Protein expression levels in different groups were analyzed using Western blot (n = 3). Data were expressed as mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.